Syphilis is a Sexually Transmitted Disease (STD), which is caused by bacterium called Treponema pallidum (sub-species pallidum). It is transmitted when a person has any kind of sexual contact with an infected individual, it can also be transmitted from a pregnant mother to the fetus (unborn child).
In 1901, the German bacteriologist Paul Ehrlich, synthesized Salvarsan , an organic compound of arsenic , designed specifically for the treatment of syphilis and it became one of the first drugs, effective in synthetic cure of infectious diseases . The Salvarsan (and its derivative neosalvarsan) were dropped from 1944, in favor of treatment with penicillin, which is way more effective.
To test the effectiveness of penicillin, during the years 1946 to 1948, the US Government conducted syphilis experiments on citizens of Guatemala and they came up results, which strengthen their belief in penicillin as the right drug for treating this disease.
Today, syphilis is easily cured with antibiotics such as penicillin, during the primary and secondary stages. Penicillin can also be used in the last stage of the disease, but the dosage has to be of g-sodium penicillin, as the sodium will help in diffusing the antibiotic to the CSF (cerebrospinal fluid), which is where the bacteria lives, during this last phase.
Sufferers of syphilis should lead a healthy life with a balanced diet and adequate sleep. The bacterium Treponema pallidum is a spirochete and can be treated with benzathine penicillin in the form of intramuscular injection.
The dosage of penicillin depends on the stage of the disease, ranging from a single dose in primary infections to schemes where it is necessary to provide multiple doses of the antibiotic (late syphilis or delayed dormant). Patients who are allergic to penicillin, can opt for other anti-biotic drugs like doxycycline , macrolides or ceftriaxone .